Editorial Scope
What we cover
Threshold Ledger provides editorial coverage and reference material — not medical care. Here is the scope of what we track.
Risk & safety
We explain the cardiac (QT) and respiratory risks of the ibogaine–methadone intersection and the screening and monitoring that responsible programs require — see cardiac risk.
Protocols & sequencing
We describe how supervised programs sequence a taper, washout and monitored dosing, and how timing is judged — see the transition and timing.
Access, legality & cost
We map where treatment is legal and what it costs, without endorsing providers — see legality & cost and finding a clinic.
Evidence & alternatives
We summarise what the research shows and how ibogaine compares to established paths — see the evidence and alternatives.